Loris
Olivier

Swiss Brain Observatory

2014_2024

What I did for this project:

Product design
Frontend engineering
Backend engineering
UX research
UI microinteraction

Summary

Add the project summary as Portable Text in Sanity (Summary). This sits under the title and outlines what the piece is about.

Challenge

Describe the constraints, risks, or problem framing (Portable Text — Challenge).

Research

Capture research, audits, interviews, or evidence that informed the work (Portable Text — Research).

Solution

Summarize what you shipped, measured, or learned — the response to the challenge (Portable Text — Solution).

Image of home page of Open brain platform
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Image of home page of Open brain platform

Image of connected home with three section
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Image of connected home with three section

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Image of a macbook mockup with the home page background
Image of an interface with a 3D brain and a title
Image of an interface with a user information box
Image of the navigation of Open Brain platform explore
Image of a double button appearing on the bottom right part of the screen
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Browse the experimental data, all the different data related to the current model and some generated during all simulation experiment. Go deeper into knowledge discovery with our literature search AI tool.

Core concept

All the way through the different iterations, the core concept has always been around the features of exploring the resources, building models at different scales and simulating those models

Image of a single cell selector
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Configuring and launching simulation experiments such as the whole brain generate an important amount of analysis and report. Many of those are visually based and can give access to high definition videos.

Image of a macbook mockup
Long side blue side panel of the explore section
Blue lateral side panel for the brain region with isocortex highlighted
Image of the header for the isocortex brain region with its cell types
Image a of four tabs label for the current brain region
image of a 3d brain region interactive box
Image of seven dataset type buttons
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Explore include both an atlas based subsection but also a literature one. In the first case, each brain region give an important amount of information concerning each region and their children.

User workshops

Neuroscience is such a vast domain of science. In itself, we have many scientist specialized in different brain regions. Conducting workshop to expose the interest of each participant was extremely helpful. Each team and members listen and enriched each other process by exposing problematic faced in their daily work. Quick prototyping give the ability to establish common ground and many different solutions

4 diagrams of visualisation data
Browser view of ME models visualisation
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A constant feature in OBP, for every scale, is the morphological-electrophysiological model (ME model)). Each neuron can benefit for that. When facing the whole brain, this is a gigantic amount of data. Three dimensional projection empower the user to understand and manipulate the parameters of each of these ME model.

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The most complex and time consuming process is the connectomic behaviour between region. In order to understand the intensity, the plasticity and other feature of connectivity, an interactive matrix working in a three dimensional fashion helps the user to navigate through all the brain region layers.

Details of Single Cell simulation
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Single neuron simulation can be done isolated from the region in one of the first scale tiers. While in the whole brain model construction, the user can define specific behaviour for every morphological type.

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The most complex and time consuming process is the connectomic behaviour between region. In order to understand the intensity, the plasticity and other feature of connectivity, an interactive matrix working in a three dimensional fashion helps the user to navigate through all the brain region layers.

Preview of the virtual lab
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In further iteration, we integrate the concept of virtual lab. This gives the user to gather is model building experiment, his simulation ones and the different elements he gather in explore. Having these in the same place opened the ability to have an AI-assisted paper writer function.

Build home
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Each virtual lab can possess a certain amount of project in which the user can isolate the perimeter of his experiment. In this context the user will be able to work on different scale such as single neuron, ion channel, microcircuit and 6 others

Single neuron analysis
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At many point of the application, the user can launch analysis in order to validate his parameters. As simulation can be quite massive, we've empower the user by giving him some control over the quality